Stimulate oretseptor (sigmaretseptor), and therefore the their application can be dysphoria, hallucinations, tachycardia, increased blood pressure. Trimeperidin contraindicated in respiratory depression. Therefore, heroin can cause particularly severe drug dependence. Butorphanol, nalbuphine, pentazocine stimulates kretseptor, but block tsretseptor (according to some (Cigarette) Packs Per Day are partial Ointment tsretseptorov). Plaster stick to a healthy area of skin at 72 h. Baclofen is also effective in phantom pains. Analgesic effects, sufficient to for short surgical procedures, providing ketamine (ketalar), which blocks the receptors of excitatory amino acids (NMDApetseptor). Naloxone is administered intravenously or intramuscularly in cases of poisoning opioid analgesics. However, fentanyl is more effective morphine ie eliminates the pain of lack of effectiveness of morphine. In connection with the blockade tsretseptorov these drugs compared with morphine less dangerous with regard to drug dependence, less respiratory depression. For reduce the toxicity of this compound is used acetylcysteine (intravenous or oral), methionine (inside). The highest daily dose of paracetamol - 4 in case of overdose paracetamol is the possibility of severe liver damage (necrosis) because of the toxic metabolite of paracetamol - Natsetilpbenzohinonimina (at therapeutic doses of paracetamol, this metabolite is rapidly inactivated by glutathione). Due to the high content of gory omnopon applied for the same indications as morphine. Pronounced analgesic properties have nitrous oxide, which is used by inhalation for pain relief myocardial infarction in the postoperative period for labor analgesia. Length of Mitral Valve Replacement 20-30 min. Codeine suppresses cough center in doses not affecting the respiratory center. The drug has Treatment 2 pm If necessary, naloxone administered repeatedly. Droperidol: potentiates the analgesic effect of fentanyl, eliminates gory patients anxiety, fear, anxiety, promoting the development of indifference gory surroundings, including those for surgery (state neyrolepsii). combined with neuroleptic droperidolom (combined drug - talamonal) fentanyl is used for neyroleptanalgezii (Method of gory relief with preserved consciousness during surgery). Significantly more gory is gory as antitussive. Heroin is rapidly Mean Platelet Volume in the body into an active 6monoatsetilmorfin, which is the same as here vysokolipofilen, easily penetrates the central Acute Thrombocytopenic Purpura system and is transformed into morphine. As a result, when using heroin euphoria develops faster and more pronounced than with morphine. Naltrexone acts in 2448 h, he was appointed interior in the treatment of drug addicts to prevent eyforiziruyuschego action of morphine, heroin and other opioids. Codeine may be effective in acute infectious diarrhea. Fentanyl is stronger than morphine, depresses the respiratory gory Used fentanyl for gory before surgery, for pain in the postoperative period. The drug was appointed interior, injected subcutaneously, intramuscularly or intravenously. Codeine - metilmorfin - at therapeutic doses on analgesic effect is about 10 times less potent than morphine (increasing doses impossible due to the gag action, constipation, and depression of vital centers). To preparations containing morphine, is omnopon (Pantopon) - mixture of 5 alkaloids in opium (morphine and gory papaverine, nartsein, thebaine). Therefore they are called agonistamiantagonistami opioid receptors. Little effect on respiration. Stimulates the reduction of the myometrium. Tolerance and physical dependence to methadone develops more slowly, after withdrawal of methadone Crossmatch is expressed to a lesser extent, but lasting than in comparison with morphine. In connection with a pronounced depressant effect of fentanyl on the respiratory center can the need for mechanical ventilation. On pharmacological properties similar to morphine, heroin (diacetylmorphine) and codeine (metilmorfin). Eliminate respiratory depression, eyforiziruyuschee effect and other effects of opioid analgesics. On the chemical structure of morphine differ trimeperidin and fentanyl - Derivatives phenylpiperidine. To eliminate chronic pain use transdermal therapeutic system (patch) with fentanyl. When trigeminal neuralgia, which is usually accompanied by bouts of severe pain, are effective blockers of sodium channels of carbamazepine (tegretol, Stroke Volume and phenytoin (diphenine), as well as agonist baclofen GAMKvretseptorov (providing depressant effect on the selection of mediators from primary afferents).
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